D.I.K.A

Crash Twinsanity differs greatly in gameplay from its predecessor Crash Bandicoot: The Wrath of Cortex. The game is now played in a free-roaming style rather than the follow-the-path gameplay of the past. His control style is pretty much the same as previous Crash games. Much like the Jak and Daxter series, Crash is accompanied by his nemesis Doctor Neo Cortex.

Crash can use Cortex as a hammer, perform a spin attack while holding on to him, throw him across gaps to activate switches, and can even use him as a snowboard in certain sections of the game known as "Humiliskate". In two places of the game, a path must be cleared for Cortex (to an a cappella rendition of Flight of the Bumblebee) as to avoid getting himself killed while running away from a swarm of bees and Evil Crash, respectively. These sections go by the name of "Doc Amok".

In the earlier levels, Crash and Cortex will fight each other (obscured by a cartoony dust cloud and stars), allowing the player to steer both of them throughout a part of a level in a section known as "Rollerbrawl". If the characters remain stationary for a while, the characters can actually be seen using a number of tortures on each other (including Cortex spanking Crash and Crash banging Cortex against the floor respectively). In some areas, only Cortex will be controlled, armed with a raygun with a limited amount of ammo. If Cortex is without ammo, he will be defenseless and will scream and panic whenever he is moved. In others, Cortex's niece, Nina Cortex, can be controlled, using her mechanical arms to get her through levels.